DNA (Deoxyribonucleic Acid) is the molecule of life—it carries the genetic instructions used in the growth, development, functioning, and reproduction of all known living organisms and many viruses.
🧬 Structure of DNA
- DNA has a double helix structure—imagine a twisted ladder.
🧱 Key Components:
- Nucleotides – The building blocks of DNA, each made of:
- Phosphate group
- Deoxyribose sugar (a 5-carbon sugar)
- Nitrogenous base (A, T, C, or G)
Nitrogenous Bases – There are four:
- Adenine (A)
- Thymine (T)
- Cytosine (C)
- Guanine (G)
🔗 Base Pairing Rules:
- A pairs with T
- C pairs with G
- (These are held together by hydrogen bonds)
Backbone:
- The sides of the ladder are made of sugar-phosphate chains, connected by phosphodiester bonds.
Double Helix:
- Two strands run in opposite directions (antiparallel).
- Discovered by Watson and Crick (1953), with crucial X-ray data from Rosalind Franklin.
🎯 Function of DNA
- DNA stores and transmits genetic information. Its main functions are:
1. Genetic Code
DNA contains genes, which are sequences of nucleotides that code for proteins.
A gene is essentially a "recipe" for making a specific protein.
2. Protein Synthesis
- DNA → RNA → Protein
- (This is called the Central Dogma of Molecular Biology)
Steps:
- Transcription: DNA is used to make messenger RNA (mRNA) in the nucleus.
- Translation: mRNA is read by ribosomes to assemble amino acids into a protein.
3. Replication
- DNA can copy itself during cell division.
- Each strand serves as a template for a new strand, ensuring that each new cell gets a complete copy of genetic material.
4. Heredity
- DNA is passed from parents to offspring.
- Variations in DNA (mutations) lead to genetic diversity, which drives evolution.
🧠 Summary Table
- Feature DNA
- Full name Deoxyribonucleic Acid
- Shape Double helix
- Subunits Nucleotides (sugar, phosphate, base)
- Bases A, T, C, G
- Base pairing A–T, C–G
- Location Mostly in the nucleus (in eukaryotes)
- Function Stores genetic information; directs protein synthesis
- Replication Semi-conservative (each new molecule has one old strand)
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